Solange Knowles has opened up about her “debilitating” battle with multiple autoimmune diseases.

The “Losing You” singer revealed in the comment field by musician Shaun Ross’ Instagram post about his Postural Orthostatic Tachycardia Syndrome (POTS) diagnosis that she also suffers from the chronic condition, as well as Sjogren’s Syndrome and Mast Cell Activation Syndrome (MCAS) since 2018.

“Sending you so much love and strength Shaun and to everyone in the comments struggling with the debilitating, confusing and lonely symptoms of POTS!” Beyoncé’s younger sister wrote.

Knowles, 38, then gave a shoutout to Dysautonomia International, a nonprofit organization that “strives to improve the lives of individuals living with autonomic nervous system disorders through research, medical education, public awareness and patient empowerment programs,” according to its website.

“The good people at @dysautonomiaintl were truly an incredible resource for me and I feel truly grateful to the spoonie community for holding me down during my times of total uncertainty!” she was giddy.

Page Six had reached out to their representatives for further comment but did not immediately hear back.

POTS affects the nervous system, according to Mayo Clinic.

“The nerves that regulate blood flow are out of balance, so not enough blood is going to the right place at the right time,” the website explains about the syndrome.

The lack of stable blood flow makes people feel lightheaded and dizzy. Sometimes they even pass out when they go from lying down to standing up.

People with Sjögren’s have an immune system that “damages the glands that produce and control moisture in your body,” per Mayo Clinic. This results in dryness in the eyes, throat, mouth and other places.

In people with MCAS, their cells release a chemical agent too often, causing allergic reactions, according to American Academy of Allergy, Asthma & Immunology.

Symptoms include swelling, difficulty breathing, low blood pressure and severe diarrhea.

In 2017, Knowles revealed that she was silent manage an unknown autonomic disorder after she was forced to cancel her New Year’s performance at the Afropunk festival in South Africa due to her systems.

“(It’s) been a journey that hasn’t been easy for me,” the “Cranes in the Sky” singer wrote in a since-deleted post. “Sometimes I feel cool, and other times not so cool at all.”

Although Knowles kept her exact diagnosis at the time, she said it was “complicated” and that she was “still learning so much.”